Professor Guo received his Master of Medicine degree from Fudan University, and his M.Sc. and Ph.D. from the University of Washington. He was Assistant and then Associate Research Scientist at University of Michigan, Associate Professor at University of Minnesota, and tenured full Professor at Medical College of Wisconsin. He also served a three-year term directorship at the Institute of Obstetric and Gynecologic Research, Shanghai Jiao Tong University. Since 2010, he has been Professor at Shanghai OB/GYN Hospital, Fudan University Shanghai College of Medicine. He also is an Adjunct professor at the Dept. of OB/GYN and Reproductive Sciences of Michigan State University College of Human Medicine, USA.

Professor Guo is a member of Faculty 1000 in Medicine since 2007 and has published over 150 research papers in international journals. He has given lectures at numerous research institutions worldwide and at professional meetings. He is credited as being the first to propose and provide evidence that endometriosis is an epigenetic disease. He served as Associate Editor for Human Reproduction for two terms, and now is an Associate Editor for Reproductive Sciences, Gynecologic and Obstetric Investigation, Journal of Endometriosis and Pelvic Pain Disorders, and Gynecology and Minimally Invasive Therapy. He is a member of the Board of Trustees of the World Endometriosis Society, the Society of Endometriosis and Uterine Disorders (SEUD), and the Asian Society of Endometriosis and Adenomyosis, and a member of the WHO Expert Working Groups (EWG3A). He is recently ranked as one of 10 top specialists in endometriosis by ExpertScape (http://www.expertscape.com/leaders/endometriosis). He is the co-founder and now the President-Elect of Asian Society of Endometriosis and Adenomyosis.